{"id":23688,"date":"2025-04-13T17:40:15","date_gmt":"2025-04-13T17:40:15","guid":{"rendered":"https:\/\/primegloballab.com\/?post_type=product&p=23688"},"modified":"2025-12-10T11:40:39","modified_gmt":"2025-12-10T11:40:39","slug":"blisters-de-clonazolam-06-mg-com-10-pellets","status":"publish","type":"product","link":"https:\/\/primegloballab.com\/pt\/comprar\/proibido\/blisters-de-clonazolam-06-mg-com-10-pellets\/","title":{"rendered":"Clonazolam 0,6 MG Blisters \u00e1 10 Pellets"},"content":{"rendered":"

Clonazolam 0,6 MG Blisters - Tienotriazolobenzodiazepina ultra-potente para investiga\u00e7\u00e3o avan\u00e7ada<\/span><\/span><\/strong><\/h1>\n

Nome do produto:<\/span><\/span><\/strong> Clonazolam 0,6 mg Pellets - Embalagem blister <\/span><\/span>
\nSubst\u00e2ncia ativa:<\/span><\/span><\/strong> Clonazolam <\/span><\/span>
\nClasse qu\u00edmica:<\/span><\/span><\/strong> Triazolobenzodiazepinas <\/span><\/span>
\nF\u00f3rmula molecular:<\/span><\/span><\/strong> C17H12ClN5O2 <\/span><\/span>
\nMassa molecular:<\/span><\/span><\/strong> 353,77 g\/mol <\/span><\/span>
\nDosagem por pastilha:<\/span><\/span><\/strong> 0,6 mg <\/span><\/span>
\nForma:<\/span><\/span><\/strong> Pellets comprimidos <\/span><\/span>
\nEmbalagem:<\/span><\/span><\/strong> Blister de 10 pastilhas <\/span><\/span>
\nIndica\u00e7\u00e3o:<\/span><\/span><\/strong> Apenas para uso laboratorial e anal\u00edtico<\/span><\/span><\/p>\n

\n

\ud83e\uddec O que \u00e9 o Clonazolam?<\/span><\/span><\/strong><\/h2>\n

O clonazolam \u00e9 um <\/span><\/span>triazolobenzodiazepina ultra-potente<\/span><\/span><\/strong> derivado do clonazepam e do alprazolam. \u00c9 conhecida pela sua <\/span><\/span>dose efectiva muito baixa<\/span><\/span><\/strong> e \u00e9 estudado em laborat\u00f3rio pela sua <\/span><\/span>potente agonismo do recetor GABA-A<\/span><\/span><\/strong> , <\/span><\/span>meia-vida longa<\/span><\/span><\/strong> , e <\/span><\/span>elevada afinidade de liga\u00e7\u00e3o<\/span><\/span><\/strong> .<\/span><\/span><\/p>\n

A dosagem de 0,6 mg em pellets \u00e9 deliberadamente baixa, dada a pot\u00eancia excecional do Clonazolam - ideal para <\/span><\/span>estudos de dosagem precisa, investiga\u00e7\u00e3o da liga\u00e7\u00e3o aos receptores<\/span><\/span><\/strong> e compara\u00e7\u00f5es dentro da classe estrutural das benzodiazepinas.<\/span><\/span><\/p>\n

\n

\u2705 Aplica\u00e7\u00f5es na investiga\u00e7\u00e3o cient\u00edfica<\/span><\/span><\/strong><\/h2>\n
    \n
  • Estudos de liga\u00e7\u00e3o aos receptores (subtipos GABA-A)<\/span><\/span><\/strong><\/li>\n
  • Estudo de rastreio farmacocin\u00e9tico (in vitro)<\/span><\/span><\/strong><\/li>\n
  • An\u00e1lise da toxicidade e da estabilidade em condi\u00e7\u00f5es laboratoriais<\/span><\/span><\/strong><\/li>\n
  • Investiga\u00e7\u00e3o comparativa de SAR em benzos e derivados de triazolo<\/span><\/span><\/strong><\/li>\n
  • Amostra de refer\u00eancia para equipamento anal\u00edtico (HPLC\/GC-MS)<\/span><\/span><\/strong><\/li>\n<\/ul>\n

    \u26a0\ufe0f Nota:<\/span><\/span><\/strong> N\u00e3o adequado para consumo humano. Apenas para utiliza\u00e7\u00e3o em instala\u00e7\u00f5es de investiga\u00e7\u00e3o acreditadas.<\/span><\/span><\/p><\/blockquote>\n

    \n

    \u26a0\ufe0f Poss\u00edveis desvantagens e riscos<\/span><\/span><\/strong><\/h2>\n
      \n
    • Limiar de dose extremamente baixo<\/span><\/span><\/strong> - risco de sobredosagem em caso de utiliza\u00e7\u00e3o incorrecta<\/span><\/span><\/li>\n
    • Dura\u00e7\u00e3o de a\u00e7\u00e3o muito longa<\/span><\/span><\/strong> - relevante para estudos de metabolismo e degrada\u00e7\u00e3o<\/span><\/span><\/li>\n
    • Forte perfil sedativo, amn\u00e9sico e relaxante muscular<\/span><\/span><\/strong><\/li>\n
    • Os regulamentos variam consoante o pa\u00eds (possivelmente regulamentados)<\/span><\/span><\/strong><\/li>\n
    • Risco de depend\u00eancia, ins\u00f3nia de retorno e perturba\u00e7\u00f5es cognitivas com a utiliza\u00e7\u00e3o indevida<\/span><\/span><\/strong><\/li>\n<\/ul>\n
      \n

      \ud83e\uddea Dados laboratoriais<\/span><\/span><\/strong><\/h2>\n\n\n\n\n\n\n\n\n\n\n\n\n\n
      Carater\u00edstica<\/span><\/span><\/th>\nEspecifica\u00e7\u00e3o<\/span><\/span><\/th>\n<\/tr>\n<\/thead>\n
      Subst\u00e2ncia ativa<\/span><\/span><\/td>\nClonazolam (pureza \u226599%, verificada por HPLC)<\/span><\/span><\/td>\n<\/tr>\n
      Formul\u00e1rio<\/span><\/span><\/td>\nPellets prensados (tamanho padr\u00e3o)<\/span><\/span><\/td>\n<\/tr>\n
      Dosagem por pastilha<\/span><\/span><\/td>\n0,6 mg<\/span><\/span><\/td>\n<\/tr>\n
      Embalagem<\/span><\/span><\/td>\nBlister de 10 pastilhas<\/span><\/span><\/td>\n<\/tr>\n
      Cor<\/span><\/span><\/td>\nAmarelo claro a bege<\/span><\/span><\/td>\n<\/tr>\n
      Solubilidade<\/span><\/span><\/td>\nMuito sol\u00favel em etanol, DMSO<\/span><\/span><\/td>\n<\/tr>\n
      Conselhos de armazenamento<\/span><\/span><\/td>\nConservar em local fresco (2-8 \u00b0C), seco e escuro.<\/span><\/span><\/td>\n<\/tr>\n
      Estabilidade<\/span><\/span><\/td>\nAt\u00e9 24 meses com armazenamento adequado<\/span><\/span><\/td>\n<\/tr>\n
      COA<\/span><\/span><\/td>\nDispon\u00edvel a pedido<\/span><\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n
      \n

      \ud83d\udca1 Casos de utiliza\u00e7\u00e3o recomendados<\/span><\/span><\/strong><\/h2>\n\n\n\n\n\n\n\n\n\n
      Dom\u00ednio de investiga\u00e7\u00e3o<\/span><\/span><\/th>\nAplica\u00e7\u00e3o<\/span><\/span><\/th>\n<\/tr>\n<\/thead>\n
      Neurofarmacologia<\/span><\/span><\/td>\nEnsaio de liga\u00e7\u00e3o nos subtipos de receptores GABA-A<\/span><\/span><\/td>\n<\/tr>\n
      Qu\u00edmica anal\u00edtica<\/span><\/span><\/td>\nValida\u00e7\u00e3o dos m\u00e9todos de dete\u00e7\u00e3o (LC-MS)<\/span><\/span><\/td>\n<\/tr>\n
      Investiga\u00e7\u00e3o SAR<\/span><\/span><\/td>\nCompara\u00e7\u00e3o com outras triazolobenzodiazepinas<\/span><\/span><\/td>\n<\/tr>\n
      Estudos de estabilidade<\/span><\/span><\/td>\nSob a influ\u00eancia da temperatura e da luz UV<\/span><\/span><\/td>\n<\/tr>\n
      Estudo de dosagem<\/span><\/span><\/td>\nAvalia\u00e7\u00e3o dos mecanismos de a\u00e7\u00e3o de doses baixas<\/span><\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n
      \n

      \u2753 Perguntas frequentes (FAQ)<\/span><\/span><\/strong><\/h2>\n

      1. Porqu\u00ea apenas 0,6 mg por pastilha?<\/span><\/span><\/strong>
      \n O clonazolam \u00e9 <\/span><\/span>muito potente<\/span><\/span><\/strong> - podem ocorrer efeitos fortes mesmo com 0,25-0,5 mg. 0,6 mg permite a realiza\u00e7\u00e3o de an\u00e1lises laboratoriais com uma margem de erro m\u00ednima.<\/span><\/span><\/p>\n

      2. O clonazolam \u00e9 legal?<\/span><\/span><\/strong>
      \n Isto depende do teu pa\u00eds ou regi\u00e3o. Em muitos pa\u00edses, \u00e9 considerada uma subst\u00e2ncia controlada. Verifique sempre a legisla\u00e7\u00e3o local antes de a utilizar ou possuir.<\/span><\/span><\/p>\n

      3. Esta subst\u00e2ncia \u00e9 adequada para uso humano? <\/span><\/span><\/strong>
      \nN\u00e3o.<\/span><\/span><\/strong> Este produto destina-se a <\/span><\/span>investiga\u00e7\u00e3o cient\u00edfica<\/span><\/span><\/strong> Qualquer outra utiliza\u00e7\u00e3o \u00e9 <\/span><\/span>inseguro e proibido<\/span><\/span><\/strong> .<\/span><\/span><\/p>\n

      4. Est\u00e1 dispon\u00edvel um certificado de an\u00e1lise (COA)?<\/span><\/span><\/strong>
      \n Sim, um <\/span><\/span>COA<\/span><\/span><\/strong> com informa\u00e7\u00f5es espec\u00edficas do lote est\u00e1 dispon\u00edvel mediante pedido.<\/span><\/span><\/p>\n

      5. Como \u00e9 que devo guardar estes granulados?<\/span><\/span><\/strong>
      \n Conservar na embalagem de origem em <\/span><\/span>um ambiente fresco, seco e escuro<\/span><\/span><\/strong> lugar. Isto manter\u00e1 os granulados est\u00e1veis e f\u00e1ceis de dosear.<\/span><\/span><\/p>\n

      \n

      \ud83d\udce6 Vis\u00e3o geral do produto<\/span><\/span><\/strong><\/h2>\n\n\n\n\n\n\n\n\n\n\n\n\n\n
      Carater\u00edstica<\/span><\/span><\/th>\nEspecifica\u00e7\u00e3o<\/span><\/span><\/th>\n<\/tr>\n<\/thead>\n
      Nome do produto<\/span><\/span><\/td>\nClonazolam 0,6 mg Comprimidos<\/span><\/span><\/td>\n<\/tr>\n
      Embalagem<\/span><\/span><\/td>\nBlister de 10 pastilhas<\/span><\/span><\/td>\n<\/tr>\n
      Formul\u00e1rio<\/span><\/span><\/td>\nPellets prensados<\/span><\/span><\/td>\n<\/tr>\n
      Dosagem<\/span><\/span><\/td>\n0,6 mg por pastilha<\/span><\/span><\/td>\n<\/tr>\n
      Pureza<\/span><\/span><\/td>\n\u226599% (confirmado por HPLC)<\/span><\/span><\/td>\n<\/tr>\n
      Estado de armazenamento<\/span><\/span><\/td>\nFrio, seco, escuro<\/span><\/span><\/td>\n<\/tr>\n
      Utiliza\u00e7\u00e3o<\/span><\/span><\/td>\nApenas para investiga\u00e7\u00e3o anal\u00edtica<\/span><\/span><\/td>\n<\/tr>\n
      Estatuto jur\u00eddico<\/span><\/span><\/td>\nDependente da regi\u00e3o<\/span><\/span><\/td>\n<\/tr>\n
      COA<\/span><\/span><\/td>\nSim, a pedido<\/span><\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

       <\/p>","protected":false},"excerpt":{"rendered":"

      Clonazolam pellets properties<\/span><\/span><\/h2>\n

      Synonym:<\/span><\/span><\/strong> 6-(2-chlorophenyl)-1-methyl-8-nitro-4H-[1,2,4]triazolo[4,3-a] [1,4]benzodiazepine <\/span><\/span>
      \nCAS Number:<\/span><\/span><\/strong> 33887-02-4 <\/span><\/span>
      \nFormula:<\/span><\/span><\/strong> C17H12C1N5O2 <\/span><\/span>
      \nMolar mass:<\/span><\/span><\/strong> 353.8 g\/mol <\/span><\/span>
      \nPurity:<\/span><\/span><\/strong> \u226598%<\/span><\/span><\/p>\n","protected":false},"featured_media":29096,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"product_brand":[82],"product_cat":[488],"product_tag":[326],"class_list":["post-23688","product","type-product","status-publish","has-post-thumbnail","product_brand-research-chemical","product_cat-verboden","product_tag-nl","first","outofstock","taxable","shipping-taxable","purchasable","product-type-simple"],"_links":{"self":[{"href":"https:\/\/primegloballab.com\/pt\/wp-json\/wp\/v2\/product\/23688","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/primegloballab.com\/pt\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/primegloballab.com\/pt\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/primegloballab.com\/pt\/wp-json\/wp\/v2\/comments?post=23688"}],"version-history":[{"count":4,"href":"https:\/\/primegloballab.com\/pt\/wp-json\/wp\/v2\/product\/23688\/revisions"}],"predecessor-version":[{"id":28053,"href":"https:\/\/primegloballab.com\/pt\/wp-json\/wp\/v2\/product\/23688\/revisions\/28053"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/primegloballab.com\/pt\/wp-json\/wp\/v2\/media\/29096"}],"wp:attachment":[{"href":"https:\/\/primegloballab.com\/pt\/wp-json\/wp\/v2\/media?parent=23688"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/primegloballab.com\/pt\/wp-json\/wp\/v2\/product_brand?post=23688"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/primegloballab.com\/pt\/wp-json\/wp\/v2\/product_cat?post=23688"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/primegloballab.com\/pt\/wp-json\/wp\/v2\/product_tag?post=23688"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}