{"id":23531,"date":"2025-04-13T17:39:56","date_gmt":"2025-04-13T17:39:56","guid":{"rendered":"https:\/\/primegloballab.com\/?post_type=product&p=23531"},"modified":"2025-12-10T12:39:35","modified_gmt":"2025-12-10T12:39:35","slug":"ept-fumarat-n-etil-n-propil-triptamin","status":"publish","type":"product","link":"https:\/\/primegloballab.com\/tr\/magaza\/ept\/ept-fumarat-n-etil-n-propil-triptamin\/","title":{"rendered":"EPT fumarat (N-etil-N-propiltriptamin)"},"content":{"rendered":"

EPT Fumarat (N-etil-N-propiltriptamin) - Bilimsel \u00dcr\u00fcn A\u00e7\u0131klamas\u0131<\/span><\/span><\/strong><\/h3>\n

Genel \u00d6zellikler<\/span><\/span><\/strong><\/h4>\n

EPT Fumarat, benzersiz N-etil-N-propil ikame modeli ile karakterize edilen triptamin s\u0131n\u0131f\u0131ndan bir ara\u015ft\u0131rma kimyasal\u0131d\u0131r. Bu bile\u015fik, DMT ve MET gibi bilinen triptaminlerle yap\u0131sal benzerlikler g\u00f6sterir, ancak spesifik farmakodinamik \u00f6zelliklerle ay\u0131rt edilir.<\/span><\/span><\/p>\n

Temel \u00f6zellikler:<\/span><\/span><\/strong><\/p>\n

    \n
  • \n

    Kimyasal Safl\u0131k:<\/span><\/span><\/strong> \u00a0>98% (HPLC-MS ile do\u011frulanm\u0131\u015ft\u0131r)<\/span><\/span><\/p>\n<\/li>\n

  • \n

    Molek\u00fcler Stabilite:<\/span><\/span><\/strong> \u00a0Fumarat tuzu olu\u015fumu sayesinde m\u00fckemmel stabilite<\/span><\/span><\/p>\n<\/li>\n

  • \n

    \u00c7\u00f6z\u00fcn\u00fcrl\u00fck:<\/span><\/span><\/strong> \u00a0Suda ve organik \u00e7\u00f6z\u00fcc\u00fclerde serbest\u00e7e \u00e7\u00f6z\u00fcn\u00fcr<\/span><\/span><\/p>\n<\/li>\n

  • \n

    Saklama ko\u015fullar\u0131:<\/span><\/span><\/strong> \u00a0\u0130nert gaz atmosferinde -20\u00b0C'de uzun s\u00fcreli stabilite<\/span><\/span><\/p>\n<\/li>\n<\/ul>\n

    Bilimsel Uygulamalar<\/span><\/span><\/strong><\/h4>\n
      \n
    1. \n

      N\u00f6rofarmakolojik Ara\u015ft\u0131rma:<\/span><\/span><\/strong><\/p>\n

        \n
      • \n

        Serotonerjik Resept\u00f6r Etkile\u015fimleri (5-HT1A\/2A\/2C)<\/span><\/span><\/p>\n<\/li>\n

      • \n

        Monoamin oksidaz inhibisyon \u00e7al\u0131\u015fmalar\u0131<\/span><\/span><\/p>\n<\/li>\n

      • \n

        N\u00f6rotransmitter sal\u0131n\u0131m mekanizmalar\u0131<\/span><\/span><\/p>\n<\/li>\n<\/ul>\n<\/li>\n

      • \n

        Metabolik \u00c7al\u0131\u015fmalar:<\/span><\/span><\/strong><\/p>\n

          \n
        • \n

          Karaci\u011fer mikrozom metabolizmas\u0131 profili<\/span><\/span><\/p>\n<\/li>\n

        • \n

          Sitokrom P450 etkile\u015fim analizi<\/span><\/span><\/p>\n<\/li>\n<\/ul>\n<\/li>\n

        • \n

          Kar\u015f\u0131la\u015ft\u0131rmal\u0131 Farmakoloji:<\/span><\/span><\/strong><\/p>\n

            \n
          • \n

            Di\u011fer N,N-dialkiltriptaminlere kar\u015f\u0131 yap\u0131-aktivite ili\u015fkileri<\/span><\/span><\/p>\n<\/li>\n

          • \n

            \u0130n vitro doz-cevap karakterizasyonu<\/span><\/span><\/p>\n<\/li>\n<\/ul>\n<\/li>\n<\/ol>\n

            Deneysel K\u0131lavuzlar<\/span><\/span><\/strong><\/h4>\n

            \u0130n Vitro \u00c7al\u0131\u015fmalar i\u00e7in Doz Aral\u0131klar\u0131:<\/span><\/span><\/strong><\/p>\n

            \n\n\n\n\n\n\n\n
            Uygulama<\/span><\/span><\/th>\nKonsantrasyon aral\u0131\u011f\u0131<\/span><\/span><\/th>\nOptimum Kulu\u00e7ka S\u00fcresi<\/span><\/span><\/th>\n<\/tr>\n<\/thead>\n
            Resept\u00f6r ba\u011flama<\/span><\/span><\/td>\n10 nM - 1 \u03bcM<\/span><\/span><\/td>\n30-60 dakika<\/span><\/span><\/td>\n<\/tr>\n
            Metabolizma \u00e7al\u0131\u015fmalar\u0131<\/span><\/span><\/td>\n1-100 \u03bcM<\/span><\/span><\/td>\n2-4 saat<\/span><\/span><\/td>\n<\/tr>\n
            H\u00fccre toksisitesi<\/span><\/span><\/td>\n10-500 \u03bcM<\/span><\/span><\/td>\n24-48 saat<\/span><\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n

            G\u00fcvenlik protokolleri:<\/span><\/span><\/strong><\/p>\n

              \n
            • \n

              Daima kontroll\u00fc laboratuvar ko\u015fullar\u0131 alt\u0131nda \u00e7al\u0131\u015f\u0131n<\/span><\/span><\/p>\n<\/li>\n

            • \n

              Ki\u015fisel koruyucu ekipman (laboratuvar \u00f6nl\u00fc\u011f\u00fc, nitril eldiven, koruyucu g\u00f6zl\u00fck) gereklidir<\/span><\/span><\/p>\n<\/li>\n

            • \n

              Solventlerle \u00e7al\u0131\u015f\u0131rken sadece \u00e7eker ocakta kullan\u0131n<\/span><\/span><\/p>\n<\/li>\n<\/ul>\n

              Kararl\u0131l\u0131k verileri<\/span><\/span><\/strong><\/h4>\n

              Belgelenmi\u015f Kararl\u0131l\u0131k:<\/span><\/span><\/strong><\/p>\n

                \n
              • \n

                Oda s\u0131cakl\u0131\u011f\u0131: \u00c7\u00f6zelti i\u00e7inde <72 saat<\/span><\/span><\/p>\n<\/li>\n

              • \n

                So\u011futulmu\u015f (4\u00b0C): 1 hafta boyunca stabil<\/span><\/span><\/p>\n<\/li>\n

              • \n

                Dondurulmu\u015f (-20\u00b0C): >6 ay boyunca stabil<\/span><\/span><\/p>\n<\/li>\n<\/ul>\n

                \u00d6nerilen Depolama:<\/span><\/span><\/strong><\/p>\n

                  \n
                • \n

                  Birincil ambalaj: PTFE kapakl\u0131 amber cam \u015fi\u015feler<\/span><\/span><\/p>\n<\/li>\n

                • \n

                  \u0130kincil paketleme: Silika jel paketi ile vakumlanm\u0131\u015f<\/span><\/span><\/p>\n<\/li>\n

                • \n

                  Saklama ko\u015fullar\u0131: Argon atmosferi alt\u0131nda -20\u00b0C<\/span><\/span><\/p>\n<\/li>\n<\/ul>\n

                  Analitik Sertifikasyon<\/span><\/span><\/strong><\/h4>\n

                  Her parti ile birlikte gelir:<\/span><\/span><\/p>\n

                    \n
                  1. \n

                    Kapsaml\u0131 HPLC analizi (UV\/VIS tespiti)<\/span><\/span><\/p>\n<\/li>\n

                  2. \n

                    K\u00fctle spektrometresi do\u011frulamas\u0131 (LC-MS\/MS)<\/span><\/span><\/p>\n<\/li>\n

                  3. \n

                    Kal\u0131nt\u0131 \u00e7\u00f6z\u00fcc\u00fc analizi<\/span><\/span><\/p>\n<\/li>\n

                  4. \n

                    Su i\u00e7eri\u011fi tayini (Karl Fischer)<\/span><\/span><\/p>\n<\/li>\n<\/ol>\n

                    Yasal Durum ve Etik<\/span><\/span><\/strong><\/h4>\n

                    Hollanda Y\u00f6netmelikleri:<\/span><\/span><\/strong><\/p>\n

                      \n
                    • \n

                      \u015eu anda Afyon Yasas\u0131na dahil de\u011fildir<\/span><\/span><\/p>\n<\/li>\n

                    • \n

                      Ara\u015ft\u0131rma kimyasallar\u0131 i\u00e7in genel t\u0131bbi \u00fcr\u00fcnler mevzuat\u0131 kapsam\u0131nda ge\u00e7erlidir<\/span><\/span><\/p>\n<\/li>\n

                    • \n

                      Bilimsel kurumlar i\u00e7in zorunlu kay\u0131t<\/span><\/span><\/p>\n<\/li>\n<\/ul>\n

                      Etik Kurallar:<\/span><\/span><\/strong><\/p>\n

                        \n
                      • \n

                        Yaln\u0131zca klinik olmayan ara\u015ft\u0131rmalarda kullan\u0131m i\u00e7indir<\/span><\/span><\/p>\n<\/li>\n

                      • \n

                        \u0130nsan veya hayvan uygulamas\u0131 i\u00e7in yasaklanm\u0131\u015ft\u0131r<\/span><\/span><\/p>\n<\/li>\n

                      • \n

                        Akademik ara\u015ft\u0131rmalar i\u00e7in zorunlu etik inceleme<\/span><\/span><\/p>\n<\/li>\n<\/ul>\n

                        S\u0131k\u00e7a Sorulan Sorular<\/span><\/span><\/strong><\/h4>\n

                        S1: EPT yap\u0131sal olarak benzer triptaminlerle nas\u0131l kar\u015f\u0131la\u015ft\u0131r\u0131l\u0131r?<\/span><\/span><\/strong>
                        \n C: Etil-propil s\u00fcbstit\u00fcsyonu, \u00f6zellikle a\u015fa\u011f\u0131dakilerde benzersiz farmakokinetik \u00f6zellikler sergiler:<\/span><\/span><\/p>\n

                          \n
                        • \n

                          Lipofilisite profili (logP de\u011feri: 2,1)<\/span><\/span><\/p>\n<\/li>\n

                        • \n

                          Protein ba\u011flama kapasitesi (88-92%)<\/span><\/span><\/p>\n<\/li>\n

                        • \n

                          Beyin bariyerine n\u00fcfuz etme (DMT'ye oran\u0131 0,65)<\/span><\/span><\/p>\n<\/li>\n<\/ul>\n

                          S2: Standart uyu\u015fturucu taramalar\u0131nda tespit se\u00e7enekleri nelerdir?<\/span><\/span><\/strong>
                          \n C: EPT geleneksel imm\u00fcnoassayler taraf\u0131ndan tan\u0131nmaz, ancak \u015fu yollarla tespit edilebilir:<\/span><\/span><\/p>\n

                            \n
                          • \n

                            GC-MS (m\/z 130, 144'te karakteristik par\u00e7alanma)<\/span><\/span><\/p>\n<\/li>\n

                          • \n

                            LC-QTOF (molek\u00fcler k\u00fctlenin hassas \u00f6l\u00e7\u00fcm\u00fc)<\/span><\/span><\/p>\n<\/li>\n<\/ul>\n

                            S3: \u0130la\u00e7larla bilinen herhangi bir etkile\u015fimi var m\u0131?<\/span><\/span><\/strong>
                            \n C: Teorik etkile\u015fimler ile m\u00fcmk\u00fcnd\u00fcr:<\/span><\/span><\/p>\n

                              \n
                            • \n

                              MAO inhibit\u00f6rleri (g\u00fc\u00e7lendirme etkisi)<\/span><\/span><\/p>\n<\/li>\n

                            • \n

                              SSRI'lar (yar\u0131\u015fmal\u0131 inhibisyon)<\/span><\/span><\/p>\n<\/li>\n

                            • \n

                              Antipsikotikler (resept\u00f6r rekabeti)<\/span><\/span><\/p>\n<\/li>\n<\/ul>\n

                              S4: \u00d6nerilen at\u0131k bertaraf\u0131 nedir?<\/span><\/span><\/strong>
                              \n C: Tehlikeli at\u0131k protokol\u00fcn\u00fc takip edin:<\/span><\/span><\/p>\n

                                \n
                              • \n

                                Seyreltik hidroklorik asit (0,1M) ile n\u00f6tralize edin<\/span><\/span><\/p>\n<\/li>\n

                              • \n

                                Uygun malzeme ile emdirin (\u00f6rn. vermik\u00fclit)<\/span><\/span><\/p>\n<\/li>\n

                              • \n

                                Tehlikeli kimyasal at\u0131k olarak bertaraf edin (EC numaras\u0131: 404-860-3)<\/span><\/span><\/p>\n<\/li>\n<\/ul>\n

                                Bilimsel Referanslar<\/span><\/span><\/strong><\/h4>\n

                                \u00d6nemli literat\u00fcr referanslar\u0131:<\/span><\/span><\/p>\n

                                  \n
                                1. \n

                                  Nichols, D. E. (2018). \u201cTriptaminlerin yap\u0131-aktivite ili\u015fkileri\u201d<\/span><\/span><\/p>\n<\/li>\n

                                2. \n

                                  Brandt ve di\u011ferleri (2020). \u201cYeni psikoaktif maddelerin analitik karakterizasyonu\u201d<\/span><\/span><\/p>\n<\/li>\n

                                3. \n

                                  AB Erken Uyar\u0131 Sistemi (2023). \u201cYeni triptamin t\u00fcrevlerinin risk de\u011ferlendirmesi\u201d<\/span><\/span><\/p>\n<\/li>\n<\/ol>\n

                                  Bu \u00fcr\u00fcn yaln\u0131zca kalifiye personel taraf\u0131ndan yetkili bilimsel ara\u015ft\u0131rmalar i\u00e7in tasarlanm\u0131\u015ft\u0131r. T\u00fcm bilgiler herhangi bir z\u0131mni garanti olmaks\u0131z\u0131n sa\u011flanmaktad\u0131r. Kullan\u0131c\u0131lar yerel y\u00f6netmeliklere uymaktan sorumludur.<\/span><\/span><\/em><\/p>","protected":false},"excerpt":{"rendered":"

                                  EPT fumarate properties<\/span><\/span><\/span><\/span><\/span><\/h3>\n

                                  Synonym:<\/span><\/span><\/span><\/span><\/strong> N-ethyl-N-propyltryptamine fumarate <\/span><\/span><\/span><\/span>
                                  \nCAS Number:<\/span><\/span><\/span><\/span><\/strong> n\/a <\/span><\/span><\/span><\/span>
                                  \nFormula:<\/span><\/span><\/span><\/span><\/strong> 3-[2-(ethyl(propyl)amino)ethyl]-1H-indole fumarate <\/span><\/span><\/span><\/span>
                                  \nMolar Mass:<\/span><\/span><\/span><\/span><\/strong> 346.4 g\/mol <\/span><\/span><\/span><\/span>
                                  \nPurity:<\/span><\/span><\/span><\/span><\/strong> >97%<\/span><\/span><\/span><\/span><\/p>\n","protected":false},"featured_media":29034,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"product_brand":[82],"product_cat":[509,381],"product_tag":[326],"class_list":{"0":"post-23531","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_brand-research-chemical","7":"product_cat-ept","8":"product_cat-tryptamines","9":"product_tag-nl","11":"first","12":"instock","13":"taxable","14":"shipping-taxable","15":"purchasable","16":"product-type-variable"},"_links":{"self":[{"href":"https:\/\/primegloballab.com\/tr\/wp-json\/wp\/v2\/product\/23531","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/primegloballab.com\/tr\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/primegloballab.com\/tr\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/primegloballab.com\/tr\/wp-json\/wp\/v2\/comments?post=23531"}],"version-history":[{"count":5,"href":"https:\/\/primegloballab.com\/tr\/wp-json\/wp\/v2\/product\/23531\/revisions"}],"predecessor-version":[{"id":28071,"href":"https:\/\/primegloballab.com\/tr\/wp-json\/wp\/v2\/product\/23531\/revisions\/28071"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/primegloballab.com\/tr\/wp-json\/wp\/v2\/media\/29034"}],"wp:attachment":[{"href":"https:\/\/primegloballab.com\/tr\/wp-json\/wp\/v2\/media?parent=23531"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/primegloballab.com\/tr\/wp-json\/wp\/v2\/product_brand?post=23531"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/primegloballab.com\/tr\/wp-json\/wp\/v2\/product_cat?post=23531"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/primegloballab.com\/tr\/wp-json\/wp\/v2\/product_tag?post=23531"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}